On Musicbeats.net you can download free instrumental beats to use for Mix-tapes, Albums, Movies, Freestyles, Dance Videos, Gamer Music, Workout Music, Rap Instrumental Downloads, Background Instrumentals for Youtube Videos, non-profit TV & Film projects, Beats for Songs and more. Based on Dead Cells Derelict Distillery-PLAZA Game Version: update 20 DLC-Soundtrack (mp3) (optional during install)-DLC: Rise of the Giant-DLC: The Bad Seed Interface Language: MULTi13 Language can be changed in game settings Repack Size: 689 MB (without soundtrack) HDD space after installation: 2 GB Repack By MR Tiny. Dead Cells - Soundtrack Part 1 by Yoann Laulan, released 10 May 2017 1. Prisoner's Awakening 3. Promenade Of The Condemned 4. Prison's Rooftop 6. The Old Sewers 12. The Cemetery 13. Conjonctivius 14. The Prison's Depths 15. Prison Theme 16.
Scientists at the Mayo Clinic, based in Minnesota, found that cells which no longer divide inside our bodies, known as senescent cells, are linked to diseases of old age, such as kidney failure and type-2 diabetes.
“What we found is as we are aging, we accumulate more and more of those dead cells,” said Jan van Deursen, chair of biochemistry and molecular biology at the Mayo Clinic and co-author on the study, as quoted by Newsweek.
He added that those cells are not “innocent bystanders.” Instead, they secrete proteins which have a negative impact on surrounding cells and deregulate those cells. They also negatively impact the functioning of organs.
Van Deursen and his team decided to remove those dead cells from the bodies of mice. This was done by genetically modifying normal mice so they would respond to a compound known as AP20187, which was originally developed as an anti-cancer drug.
“Cancer cells are stressed cells that have survived and senescent cells seem to do the same thing,” said van Deursen. In short, this meant that the AP20187 would eliminate senescent cells in mice.
The work involved a thorough knowledge of genetics and physiological testing, but the main goal was simple, according to co-author Darren Baker.
“We think these cells are bad when they accumulate. We remove them and see the consequences,” he said. “That’s how I try to explain it to my kids.”
The procedure increased the life span of the mice by 17 to 35 percent. The drug also delayed the formation of tumors and reduced age-related deterioration of several organs. In addition, the mice looked healthier and had lower levels of inflammation in fat, muscle and kidney tissue. No negative results were reported, according to van Deursen.
He went on to stress that it isn't necessary to remove all of the cellular litter for there to be some therapeutic benefits. He estimated that only about 50 to 78 percent of dead cells need to be removed for the procedure to be effective.
However, the technology for humans isn't quite there. In order for it to work, the drug would have to be taken in such large doses that it would prove intolerably and toxic.
Cells intact, DNA stable: ISS experiment shows Antarctic fungi could survive on Marshttps://t.co/1oyMjC2P4Jpic.twitter.com/FJzBGsqLeE
— RT (@RT_com) January 31, 2016But the research is a step in the right direction for human life extension; a number of pharmaceutical companies are already working on developing drugs aimed at disposing of cellular trash, and Baker and van Deursen have licensed patents to develop such drugs for a company that van Deursen co-founded.
The study, published in the journal Nature on Wednesday, was a follow-up to a 2011 study in which the same team found that eliminating senescent cells delayed the onset of diseases of old age in mice. However, that research was conducted on mice which had a genetic mutation that causes premature aging.
The third episode of The Walking Dead's seventh season made some bold musical choices as part of its story telling.
In addition to the usual dark and ominous score from Bear McCreary, Negan's Saviors both enjoyed the tunes of a few TV shows in the latest hour and used music as a method of breaking down/training prisoner of war Daryl Dixon.
First, the episode started with the opening of Who's The Boss playing on Dwight's TV screen but a different song playing as a montage of Dwight took over. As the burnt-face villain made the rounds through the Sanctuary, making himself a sandwich and taking dead Saviors' supplies, The Jam's 'A Town Called Malice' accompanied the scene.
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Next up was the music which was used to train Daryl as though her part of the Pavlov's dogs experiment. The song played on a loop several times throughout the episode. It was The Collapsable Hearts Club featuring Jim Bianco & Petra Haden for 'Easy Street.'
Finally, the song which seemed to break Daryl Dixon after days of being treated like an animal was Don McClean's 'Crying.' Daryl and Dwight seemed to have a moment of seeing eye to eye but a photo of Glenn's bashed skull paired with the emotional song suggesting tears was the straw that broke the camel's back.
0commentsThe Walking Dead has previously used music to set the tone of its scenes. Most memorably, the Governor's return was accompanied by Ben Nichols' 'Last Pale Light in the West' and Rick's raid on Negan's compound concluded with Hozier's 'Arsonist's Lullaby.'
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The Walking Dead airs Sundays at 9 p.m. ET on AMC. For complete coverage and insider info all season long, follow @BrandonDavisBD on Twitter.